Education and Positions: B.S. Clark University, 1985; Ph.D. MIT, 1993; Postdoctoral Fellow, Harvard University, 1993 – 1996; Postdoctoral Fellow, Brandeis University, 1996 – 1999; Assistant Professor of Molecular and Structural Biochemistry, North Carolina State University, 1999 – 2006; Associate Professor of Molecular and Structural Biochemistry, North Carolina State University, 2006 – 2011; Professor of Molecular and Structural Biochemistry, North Carolina State University, 2011; Professor of Chemistry and Chemical Biology, Northeastern University, 2012 – current.
Research Interests: Structural biology and biochemistry of Ras GTPases, their mutants and binding partners; Molecular mechanisms of signal transduction based on X-ray crystallography, NMR spectroscopy, enzyme kinetics and MD simulations; Use of organic solvents to probe sites of protein-protein and protein-ligand interactions by Multiple Solvent Crystal Structures (MSCS); Protein-water interactions/bioinformatics.
Honors and Awards: University of Cambridge By-Fellow, 2007; National Science Foundation CAREER Award, 2003 – 2008; Presidential Early Career Award for Scientists and Engineers (PECASE), 2003; Burroughs Wellcome Fund New Investigator Award in the Pharmacological Sciences, 2000 – 2003; American Cancer Society Postdoctoral Fellowship, 1996-1998; Mary Ingraham Bunting Institute of Radcliff College Biomedical Research Fellowship (postdoctoral), 1995 – 1996; Summa Cum Laude, 1985; ACS undergraduate research award in Chemistry, 1984; Phi Beta Kappa (junior year), 1984.
The Protein Society: Have been a member and attended several Protein Society meetings over the years starting from early in my career.
Service: NSF panel MCB, 2003 – 2017; NIH Major Instrumentation Study Section, 2006; NIH Ruth L. Kirschstein fellowships Study Section, 2010; Board of Directors for SER-CAT synchrotron beamline at APS, 2001-2007; Advisor to the Ras initiative at the NCI, 2013 – present; Consultant for pharmaceutical and biotech companies targeting Ras, 2016 – present; ASBMB Education and Professional Development Committee, 2008 – 2011; Quality Education for Minorities Workshops, 2004-2016; Advisor to the Burroughs Wellcome Fund Postdoctoral Enrichment Program (PDEP) for Underrepresented Minorities, 2015 – present; Director of Graduate Studies, Chemistry and Chemical Biology, focused on diversity and excellence in the Northeastern graduate program in Chemistry, 2013-2018; Advisor to the provost on Strategies and Tactics for Recruiting to Improve Diversity and Excellence (STRIDE) at the faculty level, 2013-2018; Organizing Committee for Women of Color in the Academy Conference, Boston 2018.
Vision Statement: I first attended the Protein Society meeting as a student. I was thrilled and inspired by the talks and discussions on various topics related to protein structure and chemistry that pushed the boundaries of my knowledge as a budding scientist. Over the years, my passion for protein science matured in two interconnected directions: 1) understanding the details that lead to the viability and diverse functions of proteins through rigorous research and 2) making sure the science is enriched by talented students from diverse backgrounds who can bring innovative perspectives to our projects. This requires relating with openness and flexibility to individual ways of learning and thinking. If elected as a Protein Society council member I would leverage my understanding of proteins to help promote and increase the national and international visibility of the Society’s journal Protein Science, while contributing to the annual meeting in ways to engage established investigators and inspire young scientists, promoting diversity in the membership to the Protein Society from both the academic and industrial settings.