Schedule At A Glance | Full Program PDF | Daily ScheduleThe Protein Society Annual Symposium 2022 (PS36)July 7 - 10, 2022 | San Francisco, California | Hilton San Francisco Union SquareWe are excited to bring you this year’s annual symposium, comprising 12 exceptional scientific sessions and nine award speakers totaling over 60 invited and contributed talks. Our program committee, chaired by Walter Chazin, has assembled a program that spans the broad range of protein science, combining critical underpinnings of the field, the latest developments and a vision into the future with career development and technical workshops as well as ample networking opportunities. This year’s symposium continues our commitment to open participation, with a number of symposium talks coming from contributed sessions and speakers across a broad range of topics.
The symposium will also feature networking tables, receptions, industry visits, DEI-themed workshops, a Protein Science Journal workshop, and much more. The final schedule and RSVPS will be open early May.
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The meeting is expected to start at 8:30 a.m. PST on July 7, and will end at 12:30 p.m. PST on July 10.
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Preliminary Program and Speakers
Plenary Session and Speakers |
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2022 TPS Award Winners |
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David Goodsell, Ph.D. Scripps Research Institute and Rutgers University 2022 Carl Brändén Winner |
Jin Zhang, Ph.D. University of California San Diego 2022 Christian B. Anfinsen Winner |
Sun Hur, Ph.D. Harvard University/Boston Children's Hospital 2022 Dorothy Crowfoot Hodgkin Winner |
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Art as a Tool for Structural Biology |
Illuminating the Biochemical Activity Architecture of the Cell |
Innate Immune Mechanism For Self Vs. Non-Self Rna Discrimination |
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Philipp Kukura, Ph.D. University of Oxford 2022 Emil Thomas Kaiser Winner |
Squire Booker, Ph.D. Penn State University 2022 Hans Neurath Winner |
Daniel Herschlag, Ph.D. Stanford University 2022 Stein & Moore Winner |
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Unravelling Biomolecular Structure, Interactions And Dynamics With Mass Photometry |
Taking a Hit for the Team: Self-sacrifice as a Strategy for tRNA Methylthiolation |
What Do We Understand About How Enzymes Work, And Why Don’t We Understand The Rest? |
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Nozomi Ando, Ph.D. Cornell University 2022 Protein Science Young Investigator Winner |
Nicolas Lux Fawzi, Ph.D. Brown University 2022 Protein Science Young Investigator Winner |
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Correlated Motions in Proteins |
Seeing the Atomic Determinants of Phase Separation in Function and Disease |
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2021 TPS Award Winners |
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David Agard, Ph.D. University of California, San Francisco 2021 Stein & Moore Winner |
Petra Fromme, Ph.D. Arizona State University 2021 Christian B. Anfinsen Winner |
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Protein Homeostasis at Atomic Resolution: A Tale of Two Chaperones |
Dynamics of Proteins Discovered by Time-resolved Studies with X-ray Free Electron Lasers |
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Session Topic 1: Synthetic Biology & Biosensing: Engineering Protein Components forCellular Tasks |
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Yvonne Chen, Ph.D. University of California Los Angeles |
Birte Höcker, Ph.D. Universität Bayreuth |
Barbara DiVentura, Ph.D. |
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Engineering Next-Generation CAR-T Cell Therapy for Cancer | Engineering Proteins to Sense Specific Small Ligands | Divide et Impera | ||
Session Topic 2: Seeing 3D Structures in Cells: Cryo-electron Tomography Blazes the Trail |
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Elizabeth Wright, Ph.D. University of Wisconsin-Madison |
Dimitry Tegunov, Ph.D. |
Daniela Nicastro, Ph.D. |
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The Science Behind Protein Cancer Health Disparities | Solving Structures Inside and Outside of Cells | Probing the Molecular Organization of Cells & Organelles Using Cryo-electron Tomography | ||
Session Topic 3: Integrating Techniques to Address Challenges in Protein Structural Biology |
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Sonja Lorenz, Ph.D. Max Planck Institute |
Mark Glover, Ph.D. University of Alberta |
Alexandre Bonvin, Ph.D. Universiteit Utrecht |
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Structural Principles Regulating the Ubiquitination Machinery | Structural Insights into the Recognition of Transcription Terminators by ProQ/FinO RNA Chaperones | Solving 3D Puzzles of Biomolecular Interactions by Integrative Modelling | ||
Session Topic 4: Imaging & Tracking of Proteins in Space and time |
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Ed Marcotte, Ph.D. |
Anthony Roberts, Ph.D. |
Adam Smith, Ph.D. |
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Tracing Proteins And Their Interactions Through Deep Evolutionary Time |
Building the Cilium with ATP-driven Molecular Motors | How Do Oncogenic Mutations Affect Receptor Tyrosine Kinase Dimerization and Function? | ||
Session Topic 5: Protein Science Addressing Health Disparities |
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Renee Reams, Ph.D. Florida A&M University |
Steve Townsend, Ph.D. Vanderbilt University |
Melissa Davis, Ph.D. Weill Cornell Medicine |
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The Science Behind Protein Cancer Health Disparities | Probing Human Milk Glycoproteins | Role of Ancestry in Tumor Biology | ||
Session Topic 6: Machine Learning in Protein Science |
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Deborah Marks, Ph.D. Harvard University |
Alexander Rives, Ph.D. New York University |
Mohammed AlQuraishi, Ph.D. Columbia University |
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Programming Biology for Acceleration of Biotherapeutics and Sustainability |
Language Modeling at the Scale of Evolution |
OpenFold: A trainable and Modular Implementation of AlphaFold2 | ||
Session Topic 7: Miniproteins: Are There Really that Many Additional Genes that We Have Been Missing? |
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Brian Kalish, Ph.D. |
Sarah Slavoff, Ph.D. |
Alan Saghatelian, Ph.D. |
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Miniproteins in the Human Brain: New Opportunities for Understanding Neurodevelopment and Disease | Functional (chemo-)proteomics of Small Open Reading Frame-Encoded Proteins | Discovery and Characterization of Novel Microproteins | ||
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Marie Brunet |
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The Coding Potential of Pseudogenes: Between Relics and New Beginnings | ||||
Session Topic 8: Celebrating 100 Antibody Drugs |
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K. Dane Wittrup, Ph.D. Massachusetts Institute of Technology |
Paul Carter, Ph.D. |
John Desjarlais, Ph.D. Xencor |
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Antibody Drug Lead Isolation and Optimization by Cell Surface Display and Flow Cytometric Screening | Engineering Bispecific Antibodies as Therapeutics | Mobilizing the Immune System With Bispecific Antibodies and Potency-tuned Cytokines | ||
Session Topic 9: Protein Phase Separation in Biomolecular Condensates |
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Tanja Mittag, Ph.D. St. Jude Children's Research Hospital |
Rebecca Berlow, Ph.D. |
Felipe Quiroz, Ph.D. |
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How Phase Separation is Encoded in Intrinsically Disordered Low-Complexity Domains |
Rewriting the Rules of Molecular Competition: Transcriptional Regulation by Intrinsically Disordered Proteins |
Dissecting Biomolecular Condensates Across Stratified Epithelial Tissues |
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Session Topic 10: Structure & Dynamics Perspectives on Enzyme Function |
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Dorothee Kern, Ph.D. Brandeis University |
Misty Kuhn, Ph.D. |
Ningkun Wang, Ph.D. San Jose State University |
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Time Travel to the Past and Future – Evolution of Energy Landscapes for Enzymes Catalysis | Elucidating the Molecular Landscape of Bacterial Gcn5-related N-acetyltransferase (GNAT) Enzymes |
The Old Dog Still Has Some New Tricks: Non Canonical Allosteric Regulation of SIRT1 |
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Session Topic 11: High Throughput Protein Science |
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Nevan Krogan, Ph.D. University of California San Francisco |
Orit Rozenblatt-Rosen, Ph.D. Genentech |
Andreas Pichlmair, Ph.D. Technical University of Munich |
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Mechanistically Understanding Disease Through Integration of Systems-level Data |
Cell Atlases as Roadmaps to Better Understand and Treat Disease | Characterizing Virus-host Interactions Using Multi-omics Approaches | ||
Session Topic 12: Protein and Ligand - A New Marriage Between an Old Couple |
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Travis Wheeler, Ph.D. University of Montana |
Jeanine Amacher, Ph.D. Western Washington University |
Sergio Hassan, Ph.D. NIH |
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An Open Source Workflow for Virtually Screening Billions of Molecules for Binding Affinity to Protein Targets |
A Comprehensive Structural View of Target Recognition in the Streptococcus Class A sortase Catalytic Mechanism |
In Search of New Antimicrobial Classes Against Drug-Resistant Pathogens |
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