The Protein Society Annual Symposium 2024 (PS38)
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TPS Award Winners Plenary Talks |
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 Dr. Schlau-Cohen will speak at PS39 in San Francisco |
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| 2023 Award Winner | Opening Plenary Speaker |
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July 22, 2024 4:00 - 7:00 p.m. | REGISTRATION |
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Industry Visits (RSVP only) (transportation not provided) AbCellera - 2 p.m. AMGEN British Columbia - 2 & 4 p.m. (2 separate tours) |
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7:30 - 8:30 p.m. | WELCOME/ORIENTATION FOR STUDENTS (RSVP only) Hosted by Dr. Margaret Stratton and Dr. Elizabeth Meiering |
| July 23, 2024 | |||||||||||||||||||||
| 7 a.m. - 5:30 p.m. | Registration Bayshore Grand Ballroom Foyer |
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| 8:30 - 8:35 a.m. | Opening and Plenary Speaker Introduction Elizabeth Meiering, University of Waterloo | President, The Protein Society Bayshore Grand Ballroom ABC |
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| 8:35 - 9:05 a.m. | Opening Plenary: David Eisenberg, Ph.D., University of California Los Angeles | The Amyloid State of Proteins: Structure, Polymorphs, Pathogenesis, and Disassembly |
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| 9:20 a.m. - 12:10 p.m. | Parallel Session 1: The Sharpest New Tools in the Box, Part 1 Bayshore Grand Ballroom ABC Session Chairs: Omid Haji-Ghassemi, University of Calgary and Nobuhiko Tokuriki, University of British Columbia |
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| 9:20 - 9:50 a.m. | Aina Cohen, Stanford University | New Opportunities to Study Protein Structure and Dynamics | ||||||||||||||||||||
| 9:50 - 10:20 a.m. | Christy Ann Thomson, AMGEN British Columbia | HT Quantitative Methods to Probe Antibody Interactions at the Primary B Cell Stage | ||||||||||||||||||||
| 10:20 - 10:35 a.m. |
Siavash Vahidi, University of Guelph | Beyond the Active Site: Exploiting Allosteric Pathways to Inhibit Human ClpP Protease |
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| 10:35 - 11 a.m. |
Coffee Break & Exhibits Featuring: EXHIBITOR WORKSHOP: Refeyn (at Refeyn Booth) |
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| 11:01 - 11:04 a.m | Caroline Brown, Yale University | A high-throughput proteome-wide platform for capturing membrane proteins in their native environment for structural and functional studies | ||||||||||||||||||||
| 11:04 - 11:07 a.m | Keiichiro Maruyama, Waseda University | Rapid Search for Functional Protein Sequences by Introducing InDels | ||||||||||||||||||||
| 11:07 - 11:10 a.m. | Shwetha Sreenivasan, University of Kansas Medical Center | Dissecting the Effects of Single Substitutions in an Evolving Viral Protease | ||||||||||||||||||||
| 11:10 - 11:40 a.m. | Sriram Subramaniam, University of British Columbia | AI, Cryo-EM and Drug Discovery: Emerging Intersections | ||||||||||||||||||||
| 11:40 a.m. -12:10 p.m. | James Fraser, UCSF | Ensemble Model Building and Refinement for Cryo-EM and X-ray Crystallography | ||||||||||||||||||||
| 9:20 a.m. - 12:10 p.m. | Parallel Session 2: Messages and Messengers Across the Membrane Stanley Park Ballroom (2nd Floor) Session Chairs: Franck Duong van Hoa, University of British Columbia and Gil Prive, Princess Margaret Cancer Center / University of Toronto |
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| 9:20 - 9:50 a.m. | Heather Pinkett, Northwestern University | Mechanistic Studies of ABC Importers | ||||||||||||||||||||
| 9:50 - 10:20 a.m. | Matthias Buck, Case Western Reserve University | Using solution NMR, AlphaFoldMultimer (& variants) as well as Coarse Grained Simulations - amazing to not so good for type-1 transmembrane proteins | ||||||||||||||||||||
| 10:20 - 10:35 a.m. | Gerd Prehna, University of Manitoba | Regulation of Streptococcus Pyogenes by the Prophage Protein Paratox | ||||||||||||||||||||
| 10:35 - 11 a.m. |
Coffee Break & Exhibits Featuring: EXHIBITOR WORKSHOP: Refeyn (at Refeyn Booth) |
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| 11:01 - 11:04 a.m. | Jennifer Sescil, University of Michigan | Temporally Gated Integration Reporter for Detecting PPIs With an Immediate Enzyme Activation | ||||||||||||||||||||
| 11:04 - 11:07 a.m. | Rachel McAllister, Yale University | Peripheral Membrane Protein Recruitment Mechanisms of Bruton’s Tyrosine Kinase Through Direct NativeMS Analysis From a Tunable Lipid Bilayer | ||||||||||||||||||||
| 11:07 - 11:10 a.m. | Sara Walters, Virginia Commonwealth University | Exploring Binding Interactions Between Glutathione Peroxidase 4 and Phosphatidylinositol Phosphates | ||||||||||||||||||||
| 11:10 - 11:40 a.m. | Denise Okafor, Penn State University | Ligand-driven Allostery and Interdomain Communication in Nuclear Receptors | ||||||||||||||||||||
| 11:40 a.m. - 12:10 p.m. | Rebecca Voorhees, Caltech | Membrane Protein Biogenesis and Quality Control | ||||||||||||||||||||
| 12:10 - 1:40 p.m. | Lunch & Exhibits (Grand Foyer and Bayshore Ballroom DEF) | ||||||||||||||||||||
| 12:15 - 1:30 p.m. |
Networking Tables (RSVP Required) NETWORKING TABLES - RSVP Required Chair: Dr. Margaret Stratton (UMass Amherst) |
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| 1:45 - 4:35 p.m. | Parallel Session 3: The Sharpest New Tools in the Box, Part 2 Bayshore Grand Ballroom ABC Sessions Chairs: Zev Ripstein, University of Manitoba and Angela Gronenborn, University of Pittsburgh |
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| 1:45 - 2:15 p.m. | Philipp Hanisch, Cube Biotech | Next-Gen Copolymers: Enabling Native Environment Stability for the Toughest Targets | ||||||||||||||||||||
| 2:15 - 2:45 p.m. | Michael Woodside, University of Alberta | Using Single-molecule Mass Photometry to Build Microscopic Kinetic Models of Protein Aggregation and Decipher the Action of Inhibitors | ||||||||||||||||||||
| 2:45 - 3 p.m. | Aitor Manteca, CIC biomaGUNE | Travelling in Time with Proteins: Directed Evolution vs. Ancestral Reconstruction | ||||||||||||||||||||
| 3 - 3:25 p.m. | Coffee Break & Exhibits Grand Foyer & Bayshore Grand Ballroom DEF |
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| 3:26 - 3:29 p.m. | Maria Zacharopoulou, University of Cambridge | Design of protein-DNA Nanostructures Against Intracellular Targets in Cancer | ||||||||||||||||||||
| 3:29 - 3:32 p.m. | Benjamin Rusell Lewis, Kings College London | Using hydrogen deuterium exchange mass spectrometry to reveal co-translational folding information of membrane protein ribosome nascent chain complexes |
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| 3:32 - 3:35 p.m. | Yufei Xiang, Icahn School of Medicine at Mount Sinai | Adaptive Multi-Epitope Targeting and Avidity-Enhanced (AMETA) Nanobody Platform: Diverse Mechanisms for Ultrapotent, Durable Antiviral Therapy |
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| 3:35 - 4:05 p.m. | Tatyana Polenova, University of Delaware | Peering into Biological Assemblies with Atomic Resolution: Magnetic Resonance and Integrative Structural Biology |
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| 4:05 - 4:35 p.m. | Daniella Goldfarb, Weizmann Institute of Sciences | Exploring Proteins’ Conformations Inside the Cell by EPR Spectroscopy |
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| 1:45 - 4:35 p.m. | Parallel Session 4: Ubiquitin in Action: From Structure to Cell Biology (Member-Designed Session) Stanley Park Ballroom (2nd Floor) Session Chairs: Donald Spratt and Prerna Sharma, Clark University and Geisinger Commonwealth School of Medicine |
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| 1:45 - 2:15 p.m. | Catherine Day, University of Otago | Regulation of RING E3 Ligases by Zinc Fingers and Ubiquitin |
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| 2:15 - 2:45 p.m. | Melissa Call, WEHI (Lorne partnership) | Mutational Profiling of SARS-CoV-2 PLpro in Human Cells Reveals Requirements for Function, Structure, and Drug Escape | ||||||||||||||||||||
| 2:45 - 3 p.m. | David Fushman, University of Maryland | Targeting Polyubiquitin Signals with Macrocyclic Peptides to Modulate Protein Degradation: Mechanisms of Selective Recognition of Long Lys48-linked Chains by Macrocyclic Peptide-inhibitors of Ubiquitin-proteasome System | ||||||||||||||||||||
| 3:00 - 3:25 p.m. | Coffee Break & Exhibits Grand Foyer & Bayshore Grand Ballroom DEF |
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| 3:26 - 3:29 p.m. | Erin Mulvey, Villanova University | Phase Separation of Polyubiquitinated Proteins in UBQLN2 Condensates Controls Substrate Fate | ||||||||||||||||||||
| 3:29- 3:32 p.m. | Jacob Leavitt, Colorado State University | A Machine Learning Approach to Designing Avidity-based Sensors for Ubiquitin-modified Nucleosomes | ||||||||||||||||||||
| 3:32 - 3:35 p.m. | Swasti Rawal, Medical University of Graz | Molecular Mechanism of caspase-9 CARD Oligomerization Using cryo-EM and NMR Spectroscopy | ||||||||||||||||||||
| 3:35 - 4:05 p.m. | Mark Hochstrasser, Yale University| Unexpected Roles for Ubiquitin in Cell Homeostasis and Endosymbiont Interactions | ||||||||||||||||||||
| 4:05 - 4:35 p.m. | Gary Shaw, Western University | Identifying Mechanisms of Ubiquitination by the E3 Ligase Parkin | ||||||||||||||||||||
| 5 - 7 p.m. | Reception: Posters and Exhibitors Grand Foyer & Bayshore Grand Ballroom DEF |
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| July 24, 2024 | |||||||||||||||||||||
| 7:30 a.m. - 5:30 p.m. | Registration Bayshore Grand Ballroom Foyer |
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| 8:10 - 9:10 a.m. |
Drug Discovery Workshop (RSVP Only) |
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| 9:20 a.m. - 12:10 p.m. | Parallel Session 5: Enlarging the Box: Using Protein Science to Tackle Grand Challenges, Part 1 Bayshore Grand Ballroom ABC Session Chairs: Cassandra Joiner, St. Olaf College and Katie Mitchell-Koch, University of Manitoba |
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| 9:20 - 9:50 a.m. | Jennifer DuBois, Montana State University | Fortifying Metalloenzymes for the Recycling Bin: Making Green Applications a Reality |
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| 9:50 - 10:20 a.m. | Possu Huang, Stanford University | A General Platform for Targeting MHC-II Antigens Via a Single Loop | ||||||||||||||||||||
| 10:20 - 10:35 a.m. | Matthew Schellenberg, Mayo Clinic | Dimerization-dependent Serine Protease Activity of FAM111A Prevents Replication Fork Stalling at Topoisomerase 1 Cleavage Complexes | ||||||||||||||||||||
| 10:35 - 11 a.m. | Coffee Break & Exhibits Grand Foyer & Bayshore Grand Ballroom DEF |
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| 11:01 - 11:04 a.m. | Vanessa Wiltsie, The University of Alabama | Identification and Structural Characterization of Small Molecule Inhibitors for the Fosfomycin Resistance Enzyme, FosA, from Pseudomonas aeruginosa | ||||||||||||||||||||
| 11:04 - 11:07 a.m. | Yancheng Li, Caltech | The Mechanism of Peptidoglycan Biosynthesis Inhibition by Phage-encoded Protein Antibiotics | ||||||||||||||||||||
| 11:07 - 11:10 a.m. | Barry Selinsky, Villanova University | Expression, Purification and Characterization of a Dual Function Dioxygenase/Peroxidase from Mycolicibacterium smegmatis | ||||||||||||||||||||
| 11:10 - 11:40 a.m | Natalie Strynadka, University of British Columbia | Structure-guided drug discovery targeting antibiotic resistance mechanisms in Staphlococcus aureus |
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| 11:40 a.m - 12:10 p.m. | Andre Berndt, University of Washington | Novel Approaches to fluorescent sensor design: High-Throughput Screening, and Machine Learning |
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| 9:20 a.m. - 12:10 p.m. | Parallel Session 6: Nature-Inspired Design: Enzymes, Transport Proteins and Others in Their Ilk Stanley Park Ballroom (2nd floor) Session Chairs: Mohammad Mazhab-Jafari, University of Toronto and Constance Jeffery, University of Illinois Chicago |
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| 9:20 - 9:50 a.m. | Steve Mayo, California Institute of Technology | Protein Design and Engineering for Translational Applications |
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| 9:50 - 10:20 a.m. | Nancy Forde, Simon Fraser University | Repurposing Non-motor Proteins to Make Novel Molecular Motors | ||||||||||||||||||||
| 10:20 - 10:35 a.m. | Huong Kratochvil, UNC Chapel Hill | Molecular Insights Into Mechanisms of Proton Transport Through de novo Designed Proton Channels | ||||||||||||||||||||
| 10:35 - 11 a.m. | Coffee Break & Exhibits Grand Foyer & Bayshore Grand Ballroom DEF |
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| 11:01 - 11:04 a.m | Karol Buda, University of British Columbia | Epistasis Underpins the Evolutionary Outcomes of Ancestral Proteins | ||||||||||||||||||||
| 11:04 - 11:07 a.m. | Jan Hendrik, VU Amsterdam | Optimized in vivo Synthesis of L‑Homophenylalanine and L‑Homotyrosine in E. coli | ||||||||||||||||||||
| 11:07 - 11:10 a.m. | Gun Woo, University of Washington | Synthetic design of overlapping genes using deep generative models of protein sequences | ||||||||||||||||||||
| 11:10 - 11:40 a.m. | Pumtiwitt McCarthy, Morgan State University | Towards Engineering New Substrate Specificities into a Meningococcal Capsule Polymerase | ||||||||||||||||||||
| 11:40 a.m. - 12:10 p.m. | Scott Prosser, University of Toronto | Exploring Unknown Regions of Protein Fold Space | ||||||||||||||||||||
| 12:10 - 1:45 p.m. | Lunch and Exhibits Open | ||||||||||||||||||||
| 12:30- 1:30 p.m. | Protein Science Journal Workshop (RSVP only) Cypress |
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| 12:30 - 1:30 p.m. | Educators' Panel (RSVP only) Oak |
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| 1:45 - 4:40 p.m. | Session 7: Enlarging the Box: Using Protein Science to Tackle Grand Challenges, Part 2 Bayshore Grand Ballroom ABC Session Chairs: Suzana Straus, University of British Columbia and Chris Snow, University of Colorado |
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| 1:45 - 2:15 p.m. | Kazuhiro Mio, National Institute of Advanced Industrial Science and Technology (AIST), Japan| Direct Observation of Membrane Protein Dynamics via Diffracted X-ray Tracking Techniques |
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| 2:15 - 2:45 p.m. | Nathanael Kuzio, University of Massachusetts Amherst | Caspase-6 Structure and Dynamics by NMR: Investigating the On-Off States of a Protease involved in Axonal Degenerative Pathways to Build Therapies for Neurodegeneration | ||||||||||||||||||||
| 2:45 - 3 p.m. | Jason Zhang, University of Washington | In Cell Biochemistry Via AI-generated de novo Protein Biosensors | ||||||||||||||||||||
| 3 - 3:25 p.m. | Coffee Break & Exhibits Grand Foyer & Bayshore Grand Ballroom DEF |
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| 3:26 - 3:29 p.m. | Paola Vottero, University of Alberta | Face to Face with Proteins: a Machine Learning Framework for COVID-19 Spike-binding Antibodies Prediction | ||||||||||||||||||||
| 3:29 - 3:32 p.m. | TBA | ||||||||||||||||||||
| 3:32 - 3:35 p.m. | Kelly Waters, Clark University | Protein-protein Interactions and Regulation of HERC2 RLDs and E6AP-ubiquitylation Involved in Cervical Cancer | ||||||||||||||||||||
| 3:35 - 4:05 p.m. | Jean-Philippe Julien, University of Toronto | Avidity and Multi-specificity Combined to Combat Viral Diversity | ||||||||||||||||||||
| 4:05 - 4:35 p.m. | Michael Hecht, Princeton University | Novel Proteins for Novel Functions | ||||||||||||||||||||
| 1:45 - 4:35 p.m. | Session 8: Crowding Inside and Outside the Cell Stanley Park Ballroom Session Chairs: Nada Lallous, University of British Columbia and Mazdak Khajehpour, University of Manitoba |
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| 1:45 - 2:15 p.m. | Felipe G. Quiroz, Emory University and Georgia Institute of Technology | High-fidelity in vivo Probing of Phase Seperation Dynamics Driven by Disordered Proteins |
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| 2:15 - 2:45 p.m. | Gary Pielak, University of North Carolina-Chapel Hill | Macromolecular Crowding in vitro and in Cells | ||||||||||||||||||||
| 2:45 - 3 p.m. | Fatema Bhinderwala, University of Pittsburgh | Exploiting 19F NMR for small GTPase Activity in Cells | ||||||||||||||||||||
| 3 - 3:25 p.m. | Coffee Break & Exhibits Grand Foyer & Bayshore Grand Ballroom DEF |
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| 3:26 - 3:29 p.m. | Elias Zaragoza, Universidad Nacional Autonoma de Mexico | CBS Hydrogen Sulfide Production, Driven by Oligomeric-dependent Substrate Selection, Regulates the Induction of UPR in Yeast | ||||||||||||||||||||
| 3:29 - 3:32 p.m. | Iman Asakereh, University of Manitoba | TMAO Effects Protein Folding via Entropy: A Case Study Using Paratox as an Ideal Model System | ||||||||||||||||||||
| 3:32 - 3:35 p.m. | Nancy Horton, University of Arizona | Structure-Function Studies of a Filament Forming Enzyme SgrAI | ||||||||||||||||||||
| 3:35 - 4:05 p.m | Jerelle Joseph, Princeton University | Computational Approaches for Understanding and Engineering Biomolecular Condensates | ||||||||||||||||||||
| 4:05 - 4:35 p.m. | Evan Spruijt, Radboud University | Phase Separation and Condensate Characteristics in Crowded Environments | ||||||||||||||||||||
| 5 - 7 p.m. | Reception: Posters and Exhibitors Grand Foyer and Bayshore Grand Ballroom DEF |
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| July 25, 2024 | |||||||||||||||||||||
| 7:30 a.m - 5:30 p.m. | Registration Bayshore Grand Ballroom Foyer |
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| 8:30 - 9:10 a.m. | TPS Business Meeting/New Member Breakfast (RSVP only) Cypress (2nd floor) |
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| 9:15 a.m. - 12:10 p.m. | Session 9: Game Changers in Imaging: Looking in 3D, Multi-color and In-life Cells Bayshore Grand Ballroom ABC Session Chairs: Robert Mothersole, Thompson Rivers University and Jenny Yang, Georgia State University |
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| 9:15 - 9:45 a.m. | Francisco Balzarotti, Research Institute of Molecular Pathology | Accessing the Nanoscale with Light | ||||||||||||||||||||
| 9:45 - 10:15 a.m. | Moitrayee Bhattacharyya, Yale University | Single-molecule Imaging to Determine Oligomeric Organization of Membrane Proteins From Native Membranes at Nanoscale-spatial Resolution |
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| 10:15 - 10:30 a.m. | Abhi Aggarwal, University of Calgary | Development of a Red-Shifted Ca2+ Fluorescent Biosensor for Imaging Neuronal Activity | ||||||||||||||||||||
| 10:30 - 11 a.m. | Coffee Break & Exhibits Grand Foyer & Bayshore Grand Ballroom DEF |
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| 11:01 - 11:04 a.m. | Aubrey Putansu, University of Michigan | An Expanded Integrator Sensor Motif for GPCR Ligand Detection | ||||||||||||||||||||
| 11:04 - 11:07 a.m. | Morito Sakuma, The University of British Columbia | Functional substate transition during enzyme evolution revealed by single-molecule measurement |
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| 11:07 - 11:10 a.m. | To Be Announced | ||||||||||||||||||||
| 11:10 - 11:40 a.m. | Aleksandra Radenovic, EPFL | | ||||||||||||||||||||
| 11:40 - 12:10 p.m. | Simon Scheuring, Weill Cornell Institute of Medicine | High-Speed Atomic Force Microscopy for Dynamic Single Molecule Structural Biology | ||||||||||||||||||||
| 9:15 a.m. - 12:10 p.m. | Session 10: Dancing With Shape-Shifting Partners Stanley Park Ballroom (2nd Floor) Session Chairs: Hannah Baughman, University of Washington Tacoma and Jean Baum, Rutgers University |
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| 9:15 - 9:45 a.m. | Lewis Kay, University of Toronto | Structural Biology: Understanding Function Requires Understanding Dynamics | ||||||||||||||||||||
| 9:45 - 10:15 a.m. | Maria Sunnerhagen, Linkoping University | Unraveling a Fuzzy Complex: N-Myc and Aurora A | ||||||||||||||||||||
| 10:15 - 10:30 a.m. | Timothy Audas, Simon Fraser University | Protein Structural Pockets Act as Intrinsic Temperature Sensors to Regulate Functional Amyloid Formation | ||||||||||||||||||||
| 10:30 - 11 a.m. |
Coffee Break & Exhibits Grand Foyer & Bayshore Grand Ballroom DEF |
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| 11:01 - 11:04 a.m. | Yingzi Xia, Johns Hopkins University | Unraveling the Complexity of Protein Folding: A Structural Characterization of Misfolded E.Coli Phosphoglycerate Kinase | ||||||||||||||||||||
| 11:04 - 11:07 a.m. | Shen Wang, National Taiwan University | Structural Basis for Recruitment of Peptidoglycan Endopeptidase MepS by Lipoprotein NlpI | ||||||||||||||||||||
| 11:07 - 11:10 a.m. | Jonathan Giudice, University of California at Berkeley | Requirements for efficient endosomal escape by designed mini-proteins | ||||||||||||||||||||
| 11:10 - 11:40 a.m. | Lauren Porter, NIH | Exploring Unknown Regions of Protein Fold Space | ||||||||||||||||||||
| 11:40 a.m. - 12:10 p.m. | Alexandra M Deaconescu, Brown University | Structural Basis for Regulation of the Enterobacterales RpoS-Driven General Stress Response | ||||||||||||||||||||
| 12:10 - 1:30 p.m. | Lunch and Exhibits Open | ||||||||||||||||||||
| 12:20 - 1:30 p.m. | Undergrad Research Session (RSVP only) Oak (2nd Floor) |
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| 12:30 - 1:30 p.m. | Diversity, Equity and Inclusion Event - Beyond the acronym- connecting DEI to your own protein science journey Cypress (2nd floor) |
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| 1:45 - 5 p.m. | Plenary Awards and Best Poster Presentations Bayshore Grand Ballroom ABC |
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| 1:45 - 2:20 p.m. | 2024 Marie Maynard Daly Award Introduction: Dr. Chuck Sanders, Vanderbilt University 2024 Marie Maynard Daly Award: Dr. Alexandra Newton, UCSD | Protein Kinase C Unbalanced: Dysregulated Signaling in Cancer vs. Neurodegeneration |
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| 2:20 - 2:55 p.m. | 2024 Emil Thomas Kaiser Award Introduction: Dr. Raquel Lieberman, Georgia Tech 2024 Emil Thomas Kaiser Award: Dr. David Craik, University of Queensland | Discovery and Applications of Cyclotides in Medicine and Agriculture |
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| 2:55 - 3:25 p.m. | 2024 Carl Branden Award Introduction: Joseph Ferrara, Rigaku Americas 2024 Carl Branden Award: Dr. Tamir Gonen, UCLA | |
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| 3:25 - 3:55 p.m. | Coffee Break & Exhibits Grand Foyer & Bayshore Grand Ballroom DEF |
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| 3:55 - 4:30 p.m. | 2024 Dorothy Crowfoot Hodgkin Award Introduction: Dr. Joanna Slusky, University of Kansas 2024 Dorothy Crowfoot Hodgkin Award: Dr. Margaret Sunde, University of Sydney |
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| 4:30 - 5 p.m. | Best Poster Competition Winners | Dr. Kay Perry and Dr. Meghan Breen | ||||||||||||||||||||
| 5 - 7 p.m. | Reception: Posters and Exhibitors Grand Foyer & Bayshore Grand Ballroom DEF |
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| 8:15 - 10:30 p.m. | Protein Science World Networking Reception & Dance (RSVP only) (limited transportation provided, starting at 8 PM from Westin Bayshore) |
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| July 26, 2024 | |||||||||||||||||||||
| 7 - 12 p.m. | Registration Bayshore Grand Ballroom Foyer |
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| 8:30 - 11:20 a.m. | Session 11: Integration of Structural Methodologies: More Than the Sum of the Parts | Bayshore Grand Ballroom ABC Session Chairs: Yulia Pustovalova, UCONN Health and Kevin Chan, Xi'an Jiaotong-Liverpool University |
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| 8:30 - 9 a.m. | Sheena Radford, University of Leeds | Building a Wall: Molecular Insights Into How Bacteria Do It | ||||||||||||||||||||
| 9 - 9:30 a.m. | Joseph Ferrara, Rigaku Americas | 3D Structure of Monoclonal Antibodies in Solution by Electron Density Topography | ||||||||||||||||||||
| 9:30 -9:45 a.m. | Naima Sharaf, Stanford University | Expression, Purification, and Characterization of Escherichia coli diacylated lipoprotein YcjN | ||||||||||||||||||||
| 9:45 - 10:10 a.m. | Coffee Break (No Exhibits) Grand Foyer |
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| 10:11 - 10:14 a.m. | Priscilla Chinchilla, Rutgers University | Intrinsically Disordered Regions of α-synuclein Fibrils Play a Critical Role in Aggregation Inhibition | ||||||||||||||||||||
| 10:14 - 10:17 a.m. | Kathryn Brewer, Vanderbilt University | Integrative Analysis of LQTS-relevant KCNQ1 Variants Reveals Unique Molecular Mechanisms of Pathogenesis | ||||||||||||||||||||
| 10:17 - 10:20 a.m | Florian Becker, University of Freiburg | Calcineurin B homologous protein 3 anchors the regulatory domain of human sodium/proton exchanger 1 to the membrane through novel target-myristoyl switch | ||||||||||||||||||||
| 10:20 - 10:50 a.m. | Andrej Sali, University of California San Francisco | From Integrative Structural Biology to Cell Biology | ||||||||||||||||||||
| 10:50 - 11:20 a.m. | Hao Wu, Harvard University | How Many Ways Can Proteins Damage Cell Membranes | ||||||||||||||||||||
| 8:30 - 11:20 a.m. | Session 12: Pre- and Post-translational Modification: Creating a Myriad of Proteins Out of One Bayshore Grand Ballroom DEF Session Chairs: John Antos, Western Washington University and Jeanine Amacher, Western Washington University |
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| 8:30 - 9 a.m. | James Galligan, University of Arizona | Quantifying the PTM Landscape Across the Proteome | ||||||||||||||||||||
| 9 - 9:30 a.m. | Roland Dunbrack, Fox Chase Cancer Center | Structural Bioinformatics of Typical Protein Kinases as the Basis of AlphaFold Models of the Entire Human Protein Kinome | ||||||||||||||||||||
| 9:30 - 9:45 a.m. | Martin Tovar-Ramirez, School of Dentistry, Oregon Health and Science University | Protein Senescence: A Biophysical Approach for Measuring Eye Lens Protein Oxidation | ||||||||||||||||||||
| 9:45 - 10:10 a.m. | Coffee Break (No Exhibits) Grand Foyer |
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| 10:11 - 10:14 a.m. | Debashree Behera, Indian institute of Science, Bangalore | Unique Properties of Mycobacterium tuberculosis σA | ||||||||||||||||||||
| 10:14 - 10:17 a.m. | Leah Roe, UC Berkley | Backbone Extension Acyl Rearrangement (BEAR) enable protein backbone editing | ||||||||||||||||||||
| 10:17 - 10:20 a.m. | Srinivas Silpi Thota, Tango Biosciences | Generation of Affinity Reagents to a Phosphoepitope of the 53BP1 Protein | ||||||||||||||||||||
| 10:20 - 10:50 a.m. | Evan Worden, Van Andel Institute | Asymmetries in Trans-histone Crosstalk |
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| 10:50 - 11:20 a.m. | Elizabeth Rhoades, University of Pennsylvania | It Takes Tau to Tangle: Functional Studies of a Dysfunctional Protein |
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| 11:30 a.m. - 12:45 p.m. | Plenary Awards and Closing Bayshore Grand Ballroom ABC |
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| 11:30 - 12 p.m. | 2023 Protein Science Young Investigator Introduction: Dr. Oluwatoyin (Toyin) Ajibola Asojo, Dartmouth Cancer Center Plenary Award | 2023 Protein Science Young Investigator Winner: Polly Fordyce, Stanford University |
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| 12 - 12:30 p.m. | 2024 Christian B. Anfisen Award Introduction: Vicki Wysocki, The Ohio State University Plenary Award | 2024 Christian B. Anfisen Winner: Neil Kelleher, Northwestern University |
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| 12:30 - 12:45 p.m. | Service Awards and Closing - Dr. Elizabeth Meiering, University of Waterloo | President, The Protein Society | ||||||||||||||||||||
| 2 - 4 p.m. | Industry Visit - Zymeworks (RSVP ONLY) (two tours - 2:15 and 3:00 PM) | Address: 114 East 4th Avenue, Suite 800, Vancouver, British Columbia (transportation not provided) | ||||||||||||||||||||